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Leptin (human) ELISA kit
Leptin, the product of the ob (obese) gene, is produced mainly in the adipose tissue, and is considered to play an important role in appetite control, fat metabolism and body weight regulation. The primary effect of leptin appears to be mediated by lep...
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Territorial Availability: Available worldwide directly through Bertin Bioreagent or your local distributor
Technical Warning: Check the Additional Items Required section of this kit booklet to verify if UltraPure Water (Milli-Q or equivalent) is needed for this assay
Product Overview: 
Leptin, the product of the ob (obese) gene, is produced mainly in the adipose tissue, and is considered to play an important role in appetite control, fat metabolism and body weight regulation. The primary effect of leptin appears to be mediated by leptin receptors expressed mainly in the hypothalamus. In humans, leptin levels correlate with body mass index (BMI) and percentage body fat, and are elevated even in obese individuals. Leptin has a dual action; it decreases the appetite and increases energy consumption. Leptin is secreted in circadian fashion with nocturnal rise in both lean and obese patients. Mutations of the ob gene resulting in leptin deficiency are the cause of obesity in the ob/ob mice suggesting that endogenous leptin can normalize body weight. In contrast, human obese subjects may have high levels of leptin, indicating a mechanism of leptin resistance.

 
Size: 96 wells
Shipping: Wet ice
Stability: Store at +4degrees; shelf life 9 months maximum after production
Application Media: Human serum, plasma and culture supernatant|1/3 dilution prior assay
Sample volume: 50 µL
Tracer: HRP
Detection Limit: 0.2 ng/mL
Standard Curve Range: 2-100 ng/mL
Custom Code: 3822000000
UNSPSC code: 41116104

주문정보

CAT.No 품명 규격 비고
A05174 Leptin (human) ELISA kit 96 wells HRP kits